One of the goals of ADNI is the collection of biospecimens, including blood, urine, and cerebrospinal fluid (CSF) from participants. Interested investigators, whether associated with an ADNI site or not, are encouraged to apply for use of this limited resource. However, use of ADNI samples for technology development or comparisons among different technologies is not recommended for well-established analysis unless there is preliminary data showing clearly superior performance.

Additionally, several analyses results performed by the ADNI Biomarker Core will be available in the Data Archive as follows:

• Homocysteine
• Species of isoprostanes
• CSF tau, sAPP? levels, BACE levels, and enzyme activity
• Plasma A? 40 and A? 42
• Other promising CSF and plasma based on ongoing multiplex immunoassay studies and mass spectrometry MRM studies

For information about access to biospecimen samples, or to apply, visit the Access Samples page. View methodology documents provided by the respective labs in the Biomarker Analysis section.

ADNI 1 Biospecimen Collection

CSF¹: CSF was not collected from everyone in ADNI-1, just those that volunteered and consented to have a lumbar puncture. Urine and blood were collected on everyone

ADNI GO Biospecimen Collection

ADNI 2 Biospecimen Collection