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1739 Total Publications

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes
Denise Harold,1,* Richard Abraham,1,* Paul Hollingworth,1,* Rebecca Sims,1 Amy Gerrish,1 Marian Hamshere,1 Jaspreet Singh Pahwa,1 Valentina Moskvina,1 Kimberley Dowzell,1 Amy Williams,1 Nicola Jones,1 Charlene Thomas,1 Alexandra Stretton,1 Angharad Morgan,1 Simon Lovestone,2 John Powell,3 Petroula Proitsi,3 Michelle K Lupton,3 Carol Brayne,4 David C. Rubinsztein,5 Michael Gill,6 Brian Lawlor,6 Aoibhinn Lynch,6 Kevin Morgan,7 Kristelle Brown,7 Peter Passmore,8 David Craig,8 Bernadette McGuinness,8 Stephen Todd,8 Clive Holmes,9 David Mann,10 A. David Smith,11 Seth Love,12 Patrick G. Kehoe,12 John Hardy,13 Simon Mead,14 Nick Fox,15 Martin Rossor,15 John Collinge,14 Wolfgang Maier,16 Frank Jessen,16 Britta Schürmann,16 Hendrik van den Bussche,17 Isabella Heuser,18 Johannes Kornhuber,19 Jens Wiltfang,20 Martin Dichgans,21,22 Lutz Frölich,23 Harald Hampel,24,25 Michael Hüll,26 Dan Rujescu,25 Alison Goate,27 John S.K. Kauwe,28 Carlos Cruchaga,27 Petra Nowotny,27 John C. Morris,27 Kevin Mayo,27 Kristel Sleegers,29,30 Karolien Bettens,29,30 Sebastiaan Engelborghs,30,31 Peter De Deyn,30,31 Christine van Broeckhoven,29,30 Gill Livingston,32 Nicholas J. Bass,32 Hugh Gurling,32 Andrew McQuillin,32 Rhian Gwilliam,33 Panagiotis Deloukas,33 Ammar Al-Chalabi,34 Christopher E. Shaw,34 Magda Tsolaki,35 Andrew Singleton,36 Rita Guerreiro,36 Thomas W. Mühleisen,37,38 Markus M. Nöthen,37,38 Susanne Moebus,39 Karl-Heinz Jöckel,39 Norman Klopp,40 H-Erich Wichmann,40,41 Minerva M. Carrasquillo,42 V. Shane Pankratz,43 Steven G. Younkin,42 Peter Holmans,1 Michael O'Donovan,1 Michael J. Owen,1,† and Julie Williams1
PMID: 19734902 ; PMCID:2845877 ; 2009; Journal Nat Genet; vol. 41; no. 10; pp. 1088–1093; doi:10.1038/ng.440
MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations
Vemuri P1, Wiste HJ, Weigand SD, Shaw LM, Trojanowski JQ, Weiner MW, Knopman DS, Petersen RC, Jack CR Jr; Alzheimer's Disease Neuroimaging Initiative.
PMID: 19636048 ; PMCID:2715210 ; 2009; Journal Neurology; vol. 73; no. 4; pp. 287-93; doi:10.1212/WNL.0b013e3181af79e5
Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease
Potkin, S. G., Guffanti, G., Lakatos, A., Turner, J. A., Kruggel, F., Fallon, J. H., … Macciardi, F.
PMID: 19668339 ; PMCID:2719581 ; 2009; Journal PloS One; vol. 4; no. 8; pp. e6501; doi:10.1371/journal.pone.0006501
Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer’s disease: implications for sequence of pathological events in Alzheimer’s disease
Jack, C. R., Lowe, V. J., Weigand, S. D., Wiste, H. J., Senjem, M. L., Knopman, D. S., … Petersen, R. C.
PMID: 19339253 ; PMCID:2677798 ; 2009; Journal Brain; vol. 132; pp. 1355-1365; doi:10.1093/brain/awp062
Relationships between biomarkers in aging and dementia
Jagust, W. J., Landau, S. M., Shaw, L. M., Trojanowski, J. Q., Koeppe, R. a., Reiman, E. M., … Mathis, C. a.
PMID: 19822868 ; PMCID:2764726 ; 2009; Journal Neurology; vol. 73; no. 15; pp. 1193-1199; doi:10.1212/WNL.0b013e3181bc010c
One-year brain atrophy evident in healthy aging.
Fjell, A. M., Walhovd, K. B., Fennema-Notestine, C., McEvoy, L. K., Hagler, D. J., Holland, D., … Dale, A. M.
2009; Journal Journal of Neuroscience; vol. 29; no. 48; pp. 15223-15231; doi:10.1523/JNEUROSCI.3252-09.2009
Automated MRI measures identify individuals with mild cognitive impairment and Alzheimers disease.
Desikan, R. S., Cabral, H. J., Hess, C. P., Dillon, W. P., Glastonbury, C. M., Weiner, M. W., … Fischl, B.
2009; Journal Brain; vol. 132; no. 8; pp. 2048-2057; doi:10.1093/brain/awp123
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations
Joyner, A. H., J, C. R., Bloss, C. S., Bakken, T. E., Rimol, L. M., Melle, I., … Dale, A. M.
PMID: 19717458 ; PMCID:2741277 ; 2009; Journal PNAS; vol. 106; no. 36; pp. 15483-15488; doi:10.1073/pnas.0901866106
Regional rates of neocortical atrophy from normal aging to early Alzheimer disease
McDonald, C. R., McEvoy, L. K., Gharapetian, L., Fennema-Notestine, C., Hagler, D. J., Holland, D., … Dale, a M.
PMID: 19667321 ; PMCID:2727145 ; 2009; Journal Neurology; vol. 73; no. 6; pp. 457-65; doi:10.1212/WNL.0b013e3181b16431