Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes
Denise Harold,1,* Richard Abraham,1,* Paul Hollingworth,1,* Rebecca Sims,1 Amy Gerrish,1 Marian Hamshere,1 Jaspreet Singh Pahwa,1 Valentina Moskvina,1 Kimberley Dowzell,1 Amy Williams,1 Nicola Jones,1 Charlene Thomas,1 Alexandra Stretton,1 Angharad Morgan,1 Simon Lovestone,2 John Powell,3 Petroula Proitsi,3 Michelle K Lupton,3 Carol Brayne,4 David C. Rubinsztein,5 Michael Gill,6 Brian Lawlor,6 Aoibhinn Lynch,6 Kevin Morgan,7 Kristelle Brown,7 Peter Passmore,8 David Craig,8 Bernadette McGuinness,8 Stephen Todd,8 Clive Holmes,9 David Mann,10 A. David Smith,11 Seth Love,12 Patrick G. Kehoe,12 John Hardy,13 Simon Mead,14 Nick Fox,15 Martin Rossor,15 John Collinge,14 Wolfgang Maier,16 Frank Jessen,16 Britta Schürmann,16 Hendrik van den Bussche,17 Isabella Heuser,18 Johannes Kornhuber,19 Jens Wiltfang,20 Martin Dichgans,21,22 Lutz Frölich,23 Harald Hampel,24,25 Michael Hüll,26 Dan Rujescu,25 Alison Goate,27 John S.K. Kauwe,28 Carlos Cruchaga,27 Petra Nowotny,27 John C. Morris,27 Kevin Mayo,27 Kristel Sleegers,29,30 Karolien Bettens,29,30 Sebastiaan Engelborghs,30,31 Peter De Deyn,30,31 Christine van Broeckhoven,29,30 Gill Livingston,32 Nicholas J. Bass,32 Hugh Gurling,32 Andrew McQuillin,32 Rhian Gwilliam,33 Panagiotis Deloukas,33 Ammar Al-Chalabi,34 Christopher E. Shaw,34 Magda Tsolaki,35 Andrew Singleton,36 Rita Guerreiro,36 Thomas W. Mühleisen,37,38 Markus M. Nöthen,37,38 Susanne Moebus,39 Karl-Heinz Jöckel,39 Norman Klopp,40 H-Erich Wichmann,40,41 Minerva M. Carrasquillo,42 V. Shane Pankratz,43 Steven G. Younkin,42 Peter Holmans,1 Michael O'Donovan,1 Michael J. Owen,1,† and Julie Williams1
PMID: 19734902
;
PMCID:2845877
; 2009; Journal Nat Genet; vol. 41; no. 10; pp. 1088–1093;
doi:10.1038/ng.440
